A systematic comparison reveals substantial differences in chromosomal versus episomal encoding of enhancer activity

Candidate enhancers can be identified on the basis of chromatin modifications, the binding of chromatin modifiers and transcription factors and cofactors, or chromatin accessibility. However, validating such candidates as bona fide enhancers requires functional characterization, typically achieved t...

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Detalles Bibliográficos
Autores principales: Inoue, Fumitaka, Kircher, Martin, Martin, Beth, Cooper, Gregory M., Witten, Daniela M., McManus, Michael T., Ahituv, Nadav, Shendure, Jay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204343/
https://www.ncbi.nlm.nih.gov/pubmed/27831498
http://dx.doi.org/10.1101/gr.212092.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204343/
https://www.ncbi.nlm.nih.gov/pubmed/27831498
http://dx.doi.org/10.1101/gr.212092.116

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