Evolutionary patterns of metazoan microRNAs reveal targeting principles in the let-7 and miR-10 families

MicroRNAs (miRNAs) regulate gene output by targeting degenerate elements in mRNAs and have undergone drastic expansions in higher metazoan genomes. The evolutionary advantage of maintaining copies of highly similar miRNAs is not well understood, nor is it clear what unique functions, if any, miRNA f...

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Detalles Bibliográficos
Autores principales: Wolter, Justin M., Le, Hoai Huang Thi, Linse, Alexander, Godlove, Victoria A., Nguyen, Thuy-Duyen, Kotagama, Kasuen, Lynch, Alissa, Rawls, Alan, Mangone, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204344/
https://www.ncbi.nlm.nih.gov/pubmed/27927717
http://dx.doi.org/10.1101/gr.209361.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204344/
https://www.ncbi.nlm.nih.gov/pubmed/27927717
http://dx.doi.org/10.1101/gr.209361.116

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