Large-scale mapping of gene regulatory logic reveals context-dependent repression by transcriptional activators

Transcription factors (TFs) are key mediators that propagate extracellular and intracellular signals through to changes in gene expression profiles. However, the rules by which promoters decode the amount of active TF into target gene expression are not well understood. To determine the mapping betw...

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Detalles Bibliográficos
Autores principales: van Dijk, David, Sharon, Eilon, Lotan-Pompan, Maya, Weinberger, Adina, Segal, Eran, Carey, Lucas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204347/
https://www.ncbi.nlm.nih.gov/pubmed/27965290
http://dx.doi.org/10.1101/gr.212316.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204347/
https://www.ncbi.nlm.nih.gov/pubmed/27965290
http://dx.doi.org/10.1101/gr.212316.116

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