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p38MAPK builds a hyaluronan cancer niche to drive lung tumorigenesis

Expansion of neoplastic lesions generates the initial signal that instigates the creation of a tumor niche. Nontransformed cell types within the microenvironment continuously coevolve with tumor cells to promote tumorigenesis. Here, we identify p38MAPK as a key component of human lung cancer, and sp...

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Detalles Bibliográficos
Autores principales: Brichkina, Anna, Bertero, Thomas, Loh, Hui Mun, Nguyen, Nguyet Thi Minh, Emelyanov, Alexander, Rigade, Sidwell, Ilie, Marius, Hofman, Paul, Gaggioli, Cedric, Bulavin, Dmitry V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204354/
https://www.ncbi.nlm.nih.gov/pubmed/28007785
http://dx.doi.org/10.1101/gad.290346.116