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Nitrosylation of Nitric‐Oxide‐Sensing Regulatory Proteins Containing [4Fe‐4S] Clusters Gives Rise to Multiple Iron–Nitrosyl Complexes

The reaction of protein‐bound iron–sulfur (Fe‐S) clusters with nitric oxide (NO) plays key roles in NO‐mediated toxicity and signaling. Elucidation of the mechanism of the reaction of NO with DNA regulatory proteins that contain Fe‐S clusters has been hampered by a lack of information about the natu...

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Detalles Bibliográficos
Autores principales: Serrano, Pauline N., Wang, Hongxin, Crack, Jason C., Prior, Christopher, Hutchings, Matthew I., Thomson, Andrew J., Kamali, Saeed, Yoda, Yoshitaka, Zhao, Jiyong, Hu, Michael Y., Alp, Ercan E., Oganesyan, Vasily S., Le Brun, Nick E., Cramer, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204455/
https://www.ncbi.nlm.nih.gov/pubmed/27778474
http://dx.doi.org/10.1002/anie.201607033