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The influence of p53 mutation status on the anti-cancer effect of cisplatin in oral squamous cell carcinoma cell lines

OBJECTIVES: The purpose of this study was to evaluate the anti-cancer activity of cisplatin by studying its effects on cell viability and identifying the mechanisms underlying the induction of cell cycle arrest and apoptosis on oral squamous cell carcinoma (OSCC) cell lines with varying p53 mutation...

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Detalles Bibliográficos
Autores principales: Jo, Deuk-Won, Kim, Young-Kyun, Yun, Pil-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Oral and Maxillofacial Surgeons 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206238/
https://www.ncbi.nlm.nih.gov/pubmed/28053903
http://dx.doi.org/10.5125/jkaoms.2016.42.6.337