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Th2 responses are primed by skin dendritic cells with distinct transcriptional profiles

The dendritic cell signals required for the in vivo priming of IL-4–producing T cells are unknown. We used RNA sequencing to characterize DCs from skin LN of mice exposed to two different Th2 stimuli: the helminth parasite Nippostrongylus brasiliensis (Nb) and the contact sensitizer dibutyl phthalat...

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Detalles Bibliográficos
Autores principales: Connor, Lisa M., Tang, Shiau-Choot, Cognard, Emmanuelle, Ochiai, Sotaro, Hilligan, Kerry L., Old, Samuel I., Pellefigues, Christophe, White, Ruby F., Patel, Deepa, Smith, Adam Alexander T., Eccles, David A., Lamiable, Olivier, McConnell, Melanie J., Ronchese, Franca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206495/
https://www.ncbi.nlm.nih.gov/pubmed/27913566
http://dx.doi.org/10.1084/jem.20160470