Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD

Chronic obstructive pulmonary disease (COPD) is a leading cause of death worldwide. One main pathological feature of COPD is the loss of functional alveolar tissue without adequate repair (emphysema), yet the underlying mechanisms are poorly defined. Reduced WNT–β-catenin signaling is linked to impa...

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Detalles Bibliográficos
Autores principales: Baarsma, Hoeke A., Skronska-Wasek, Wioletta, Mutze, Kathrin, Ciolek, Florian, Wagner, Darcy E., John-Schuster, Gerrit, Heinzelmann, Katharina, Günther, Andreas, Bracke, Ken R., Dagouassat, Maylis, Boczkowski, Jorge, Brusselle, Guy G., Smits, Ron, Eickelberg, Oliver, Yildirim, Ali Ö., Königshoff, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206496/
https://www.ncbi.nlm.nih.gov/pubmed/27979969
http://dx.doi.org/10.1084/jem.20160675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206496/
https://www.ncbi.nlm.nih.gov/pubmed/27979969
http://dx.doi.org/10.1084/jem.20160675

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