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Resetting microbiota by Lactobacillus reuteri inhibits T reg deficiency–induced autoimmunity via adenosine A(2A) receptors

Regulatory T (T reg) cell deficiency causes lethal, CD4(+) T cell–driven autoimmune diseases. Stem cell transplantation is used to treat these diseases, but this procedure is limited by the availability of a suitable donor. The intestinal microbiota drives host immune homeostasis by regulating the d...

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Detalles Bibliográficos
Autores principales: He, Baokun, Hoang, Thomas K., Wang, Ting, Ferris, Michael, Taylor, Christopher M., Tian, Xiangjun, Luo, Meng, Tran, Dat Q., Zhou, Jain, Tatevian, Nina, Luo, Fayong, Molina, Jose G., Blackburn, Michael R., Gomez, Thomas H., Roos, Stefan, Rhoads, J. Marc, Liu, Yuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206500/
https://www.ncbi.nlm.nih.gov/pubmed/27994068
http://dx.doi.org/10.1084/jem.20160961