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Interferon-Induced Transmembrane Protein 3 Inhibits Hantaan Virus Infection, and Its Single Nucleotide Polymorphism rs12252 Influences the Severity of Hemorrhagic Fever with Renal Syndrome

Hantaan virus (HTNV) causes hemorrhagic fever with renal syndrome (HFRS). Previous studies have identified interferon-induced transmembrane proteins (IFITMs) as an interferon-stimulated gene family. However, the role of IFITMs in HTNV infection is unclear. In this study, we observed that IFITM3 sing...

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Detalles Bibliográficos
Autores principales: Xu-yang, Zheng, Pei-yu, Bian, Chuan-tao, Ye, Wei, Ye, Hong-wei, Ma, Kang, Tang, Chun-mei, Zhang, Ying-feng, Lei, Xin, Wei, Ping-zhong, Wang, Chang-xing, Huang, Xue-fan, Bai, Ying, Zhang, Zhan-sheng, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206578/
https://www.ncbi.nlm.nih.gov/pubmed/28096800
http://dx.doi.org/10.3389/fimmu.2016.00535