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Induced pluripotent stem cell generation from a man carrying a complex chromosomal rearrangement as a genetic model for infertility studies

Despite progress in human reproductive biology, the cause of male infertility often remains unknown, due to the lack of appropriate and convenient in vitro models of meiosis. Induced pluripotent stem cells (iPSCs) derived from the cells of infertile patients could provide a gold standard model for g...

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Detalles Bibliográficos
Autores principales: Mouka, Aurélie, Izard, Vincent, Tachdjian, Gérard, Brisset, Sophie, Yates, Frank, Mayeur, Anne, Drévillon, Loïc, Jarray, Rafika, Leboulch, Philippe, Maouche-Chrétien, Leila, Tosca, Lucie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206619/
https://www.ncbi.nlm.nih.gov/pubmed/28045072
http://dx.doi.org/10.1038/srep39760