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Nucleocapsid Interacts with NPM1 and Protects it from Proteolytic Cleavage, Enhancing Cell Survival, and is Involved in PEDV Growth

Porcine epidemic diarrhea virus (PEDV) replicates in the cytoplasm of infected cells, but its nucleocapsid (N) protein localizes specifically to the nucleolus. The mechanism of nuclear translocation, and whether N protein associates with particular nucleolar components, is unknown. In this study, we...

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Detalles Bibliográficos
Autores principales: Shi, Da, Shi, Hongyan, Sun, Dongbo, Chen, Jianfei, Zhang, Xin, Wang, Xiaobo, Zhang, Jialin, Ji, Zhaoyang, Liu, Jianbo, Cao, Liyan, Zhu, Xiangdong, Yuan, Jing, Dong, Hui, Wang, Xin, Chang, Tiecheng, Liu, Ye, Feng, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206633/
https://www.ncbi.nlm.nih.gov/pubmed/28045037
http://dx.doi.org/10.1038/srep39700