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PDLIM5 links kidney anion exchanger 1 (kAE1) to ILK and is required for membrane targeting of kAE1

Anion exchanger 1 (AE1) mediates Cl(−)/HCO(3)(−) exchange in erythrocytes and kidney intercalated cells where it functions to maintain normal bodily acid-base homeostasis. AE1’s C-terminal tail (AE1C) contains multiple potential membrane targeting/retention determinants, including a predicted PDZ bi...

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Detalles Bibliográficos
Autores principales: Su, Ya, Hiemstra, Thomas F., Yan, Yahui, Li, Juan, Karet, Hannah I., Rosen, Lawrence, Moreno, Pablo, Frankl, Fiona E. Karet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206653/
https://www.ncbi.nlm.nih.gov/pubmed/28045035
http://dx.doi.org/10.1038/srep39701