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Chlorogenic acid inhibits glioblastoma growth through repolarizating macrophage from M2 to M1 phenotype

Glioblastoma is an aggressive tumor that is associated with distinctive infiltrating microglia/macrophages populations. Previous studies demonstrated that chlorogenic acid (5-caffeoylquinic acid, CHA), a phenolic compound with low molecular weight, has an anti-tumor effect in multiple malignant tumo...

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Detalles Bibliográficos
Autores principales: Xue, Nina, Zhou, Qin, Ji, Ming, Jin, Jing, Lai, Fangfang, Chen, Ju, Zhang, Mengtian, Jia, Jing, Yang, Huarong, Zhang, Jie, Li, Wenbin, Jiang, Jiandong, Chen, Xiaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206721/
https://www.ncbi.nlm.nih.gov/pubmed/28045028
http://dx.doi.org/10.1038/srep39011