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The Three-Herb Formula Shuang-Huang-Lian stabilizes mast cells through activation of mitochondrial calcium uniporter

Mast cells (MCs) are key effector cells of IgE-FcεRI- or MrgprX2-mediated signaling event. Shuang-Huang-Lian (SHL), a herbal formula from Chinese Pharmacopoeia, has been clinically used in type I hypersensitivity. Our previous study demonstrated that SHL exerted a non-negligible effect on MC stabili...

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Detalles Bibliográficos
Autores principales: Gao, Yuan, Hou, Rui, Fei, Qiaoling, Fang, Lei, Han, Yixin, Cai, Runlan, Peng, Cheng, Qi, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206722/
https://www.ncbi.nlm.nih.gov/pubmed/28045016
http://dx.doi.org/10.1038/srep38736