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Local alignment vectors reveal cancer cell-induced ECM fiber remodeling dynamics

Invasive cancer cells interact with the surrounding extracellular matrix (ECM), remodeling ECM fiber network structure by condensing, degrading, and aligning these fibers. We developed a novel local alignment vector analysis method to quantitatively measure collagen fiber alignment as a vector field...

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Detalles Bibliográficos
Autores principales: Lee, Byoungkoo, Konen, Jessica, Wilkinson, Scott, Marcus, Adam I., Jiang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206731/
https://www.ncbi.nlm.nih.gov/pubmed/28045069
http://dx.doi.org/10.1038/srep39498