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Tetramethyl Pyrazine Protects Hippocampal Neurons Against Anoxia/Reoxygenation Injury Through Inhibiting Apoptosis Mediated by JNK/MARK Signal Pathway

BACKGROUND: Tetramethyl pyrazine (TMP) is a typical biologically active alkaloid isolated from the Chinese herb Ligusticum walliichi. It has been reported that TMP shows neuroprotective and stroke injury reductive properties in cerebral ischemia/reperfusion (I/R) animal models. In the present study...

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Detalles Bibliográficos
Autores principales: Zhong, Ming, Ma, Wuhua, Zhang, Xiong, Wang, Yong, Gao, Xiaoqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207017/
https://www.ncbi.nlm.nih.gov/pubmed/28009855
http://dx.doi.org/10.12659/MSM.898921