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Fc Engineering Approaches to Enhance the Agonism and Effector Functions of an Anti-OX40 Antibody
Agonistic antibodies directed against immunostimulatory receptors belonging to the tumor necrosis factor receptor (TNFR) superfamily are emerging as promising cancer immunotherapies. Several Fc engineering approaches discovered recently can augment the anti-tumor activities of TNFR antibodies by enh...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207143/ https://www.ncbi.nlm.nih.gov/pubmed/27856634 http://dx.doi.org/10.1074/jbc.M116.757773 |