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Fc Engineering Approaches to Enhance the Agonism and Effector Functions of an Anti-OX40 Antibody

Agonistic antibodies directed against immunostimulatory receptors belonging to the tumor necrosis factor receptor (TNFR) superfamily are emerging as promising cancer immunotherapies. Several Fc engineering approaches discovered recently can augment the anti-tumor activities of TNFR antibodies by enh...

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Detalles Bibliográficos
Autores principales:	Zhang, Di, Goldberg, Monica V., Chiu, Mark L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2016
Materias:	Molecular Bases of Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207143/ https://www.ncbi.nlm.nih.gov/pubmed/27856634 http://dx.doi.org/10.1074/jbc.M116.757773

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