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Effects of multiple-dose ponesimod, a selective S1P(1) receptor modulator, on lymphocyte subsets in healthy humans

This study investigated the effects of ponesimod, a selective S1P(1) receptor modulator, on T lymphocyte subsets in 16 healthy subjects. Lymphocyte subset proportions and absolute numbers were determined at baseline and on Day 10, after once-daily administration of ponesimod (10 mg, 20 mg, and 40 mg...

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Detalles Bibliográficos
Autores principales: Jurcevic, Stipo, Juif, Pierre-Eric, Hamid, Colleen, Greenlaw, Roseanna, D’Ambrosio, Daniele, Dingemanse, Jasper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207338/
https://www.ncbi.nlm.nih.gov/pubmed/28096659
http://dx.doi.org/10.2147/DDDT.S120399