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Plastic germline reprogramming of heritable small RNAs enables maintenance or erasure of epigenetic memories
In Caenorhabditis elegans small RNAs can regulate genes across generations. The mysterious tendency of heritable RNA interference (RNAi) responses to terminate after 3–5 generations has been referred to as “the bottleneck to RNAi inheritance.” We have recently shown that the re-setting of epigenetic...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207387/ https://www.ncbi.nlm.nih.gov/pubmed/27592591 http://dx.doi.org/10.1080/15476286.2016.1229732 |