Effects on P-Glycoprotein Expression after Blood-Brain Barrier Disruption Using Focused Ultrasound and Microbubbles

Many blood-borne substances attempting to pass through the luminal membrane of brain endothelial cells are acted upon by a variety of metabolizing enzymes or are actively expelled back into the capillary lumen by embedded efflux transporters, such as Permeability-glycoprotein (Pgp). Overexpression o...

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Detalles Bibliográficos
Autores principales: Aryal, Muna, Fischer, Krisztina, Gentile, Caroline, Gitto, Salvatore, Zhang, Yong-Zhi, McDannold, Nathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207445/
https://www.ncbi.nlm.nih.gov/pubmed/28045902
http://dx.doi.org/10.1371/journal.pone.0166061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207445/
https://www.ncbi.nlm.nih.gov/pubmed/28045902
http://dx.doi.org/10.1371/journal.pone.0166061

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