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Sphingosine 1-Phosphate Receptor Modulators and Drug Discovery
Initial discovery on sphingosine 1-phosphate (S1P) as an intracellular second messenger was faced unexpectedly with roles of S1P as a first messenger, which subsequently resulted in cloning of its G protein-coupled receptors, S1P(1–5). The molecular identification of S1P receptors opened up a new av...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Korean Society of Applied Pharmacology
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207465/ https://www.ncbi.nlm.nih.gov/pubmed/28035084 http://dx.doi.org/10.4062/biomolther.2016.160 |