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Methylation profiles of thirty four promoter-CpG islands and concordant methylation behaviours of sixteen genes that may contribute to carcinogenesis of astrocytoma

BACKGROUND: Astrocytoma is a common aggressive intracranial tumor and presents a formidable challenge in the clinic. Association of altered DNA methylation patterns of the promoter CpG islands with the expression profile of cancer-related genes, has been found in many human tumors. Therefore, DNA me...

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Detalles Bibliográficos
Autores principales: Yu, Jian, Zhang, Hongyu, Gu, Jun, Lin, Song, Li, Junhua, Lu, Wei, Wang, Yifei, Zhu, Jingde
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC520749/
https://www.ncbi.nlm.nih.gov/pubmed/15367334
http://dx.doi.org/10.1186/1471-2407-4-65