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Altered Epithelial Gene Expression in Peripheral Airways of Severe Asthma

Management of severe asthma remains a challenge despite treatment with glucocorticosteroid therapy. The majority of studies investigating disease mechanisms in treatment-resistant severe asthma have previously focused on the large central airways, with very few utilizing transcriptomic approaches. T...

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Detalles Bibliográficos
Autores principales: Singhania, Akul, Rupani, Hitasha, Jayasekera, Nivenka, Lumb, Simon, Hales, Paul, Gozzard, Neil, Davies, Donna E., Woelk, Christopher H., Howarth, Peter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207492/
https://www.ncbi.nlm.nih.gov/pubmed/28045928
http://dx.doi.org/10.1371/journal.pone.0168680