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Single Cell Mathematical Model Successfully Replicates Key Features of GBM: Go-Or-Grow Is Not Necessary

Glioblastoma (GBM) is a malignant brain tumor that continues to be associated with neurological morbidity and poor survival times. Brain invasion is a fundamental property of malignant glioma cells. The Go-or-Grow (GoG) phenotype proposes that cancer cell motility and proliferation are mutually excl...

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Detalles Bibliográficos
Autores principales: Scribner, Elizabeth, Fathallah-Shaykh, Hassan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207515/
https://www.ncbi.nlm.nih.gov/pubmed/28046101
http://dx.doi.org/10.1371/journal.pone.0169434