Iron Supplementation Reverses the Reduction of Hydroxymethylcytosine in Hepatic DNA Associated With Chronic Alcohol Consumption in Rats

BACKGROUND: Alcohol is known to affect two epigenetic phenomena, DNA methylation and DNA hydroxymethylation, and iron is a cofactor of ten-eleven translocation (TET) enzymes that catalyze the conversion from methylcytosine to hydroxymethylcytosine. In the present study we aimed to determine the effe...

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Detalles Bibliográficos
Autores principales: Tammen, Stephanie A., Park, Jung Eun, Shin, Phil Kyung, Friso, Simonetta, Chung, Jayong, Choi, Sang-Woon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Cancer Prevention 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207611/
https://www.ncbi.nlm.nih.gov/pubmed/28053961
http://dx.doi.org/10.15430/JCP.2016.21.4.264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207611/
https://www.ncbi.nlm.nih.gov/pubmed/28053961
http://dx.doi.org/10.15430/JCP.2016.21.4.264

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