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Detoxification of Mitochondrial Oxidants and Apoptotic Signaling Are Facilitated by Thioredoxin-2 and Peroxiredoxin-3 during Hyperoxic Injury

Mitochondria play a fundamental role in the regulation of cell death during accumulation of oxidants. High concentrations of atmospheric oxygen (hyperoxia), used clinically to treat tissue hypoxia in premature newborns, is known to elicit oxidative stress and mitochondrial injury to pulmonary epithe...

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Detalles Bibliográficos
Autores principales: Forred, Benjamin J., Daugaard, Darwin R., Titus, Brianna K., Wood, Ryan R., Floen, Miranda J., Booze, Michelle L., Vitiello, Peter F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207683/
https://www.ncbi.nlm.nih.gov/pubmed/28045936
http://dx.doi.org/10.1371/journal.pone.0168777