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Detoxification of Mitochondrial Oxidants and Apoptotic Signaling Are Facilitated by Thioredoxin-2 and Peroxiredoxin-3 during Hyperoxic Injury
Mitochondria play a fundamental role in the regulation of cell death during accumulation of oxidants. High concentrations of atmospheric oxygen (hyperoxia), used clinically to treat tissue hypoxia in premature newborns, is known to elicit oxidative stress and mitochondrial injury to pulmonary epithe...
Autores principales: | Forred, Benjamin J., Daugaard, Darwin R., Titus, Brianna K., Wood, Ryan R., Floen, Miranda J., Booze, Michelle L., Vitiello, Peter F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207683/ https://www.ncbi.nlm.nih.gov/pubmed/28045936 http://dx.doi.org/10.1371/journal.pone.0168777 |
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