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Pharmaceutical Metabolism in Fish: Using a 3-D Hepatic In Vitro Model to Assess Clearance

At high internal doses, pharmaceuticals have the potential for inducing biological/pharmacological effects in fish. One particular concern for the environment is their potential to bioaccumulate and reach pharmacological levels; the study of these implications for environmental risk assessment has t...

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Detalles Bibliográficos
Autores principales: Baron, Matthew G., Mintram, Kate S., Owen, Stewart F., Hetheridge, Malcolm J., Moody, A. John, Purcell, Wendy M., Jackson, Simon K., Jha, Awadhesh N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207725/
https://www.ncbi.nlm.nih.gov/pubmed/28045944
http://dx.doi.org/10.1371/journal.pone.0168837