Cell-Free DNA Provides a Good Representation of the Tumor Genome Despite Its Biased Fragmentation Patterns

Cell-free DNA (cfDNA) is short, extracellular, fragmented double-stranded DNA found in plasma. Plasma of patients with solid tumor has been found to show significantly increased quantities of cfDNA. Although currently poorly understood, the mechanism of cfDNA generation is speculated to be a product...

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Detalles Bibliográficos
Autores principales: Ma, Xiangyuan, Zhu, Liangjun, Wu, Xue, Bao, Hua, Wang, Xiaonan, Chang, Zhili, Shao, Yang W., Wang, Zhenxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207727/
https://www.ncbi.nlm.nih.gov/pubmed/28046008
http://dx.doi.org/10.1371/journal.pone.0169231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207727/
https://www.ncbi.nlm.nih.gov/pubmed/28046008
http://dx.doi.org/10.1371/journal.pone.0169231

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