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Changes of Ovarian microRNA Profile in Long-Living Ames Dwarf Mice during Aging

The Ames dwarf (df/df) mice have extended longevity and can preserve the ovarian reserve longer than Normal (N) mice. Based on this, the aim of our study was to evaluate the ovarian microRNA (miRNA) profile in young and aged df/df and N mice. Ovarian tissue was collected at 5–6 months and at 21–22 m...

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Detalles Bibliográficos
Autores principales: Schneider, Augusto, Matkovich, Scot J., Victoria, Berta, Spinel, Lina, Bartke, Andrzej, Golusinski, Pawel, Masternak, Michal M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207734/
https://www.ncbi.nlm.nih.gov/pubmed/28046124
http://dx.doi.org/10.1371/journal.pone.0169213