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Detection and interpretation of shared genetic influences on 42 human traits

We performed a scan for genetic variants associated with multiple phenotypes by comparing large genome-wide association studies (GWAS) of 42 traits or diseases. We identified 341 loci (at an FDR of 10%) associated with multiple traits. Several loci are associated with a large number of phenotypes; f...

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Detalles Bibliográficos
Autores principales: Pickrell, Joseph K., Berisa, Tomaz, Liu, Jimmy Z., Segurel, Laure, Tung, Joyce Y., Hinds, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207801/
https://www.ncbi.nlm.nih.gov/pubmed/27182965
http://dx.doi.org/10.1038/ng.3570