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Endoplasmic reticulum degradation impedes olfactory G-protein coupled receptor functional expression

BACKGROUND: Research on olfactory G-protein coupled receptors (GPCRs) has been severely impeded by poor functional expression in heterologous systems. Previously, we demonstrated that inefficient olfactory receptor (OR) expression at the plasma membrane is attributable, in part, to degradation of en...

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Detalles Bibliográficos
Autores principales: Lu, Min, Staszewski, Lena, Echeverri, Fernando, Xu, Hong, Moyer, Bryan D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC520810/
https://www.ncbi.nlm.nih.gov/pubmed/15369603
http://dx.doi.org/10.1186/1471-2121-5-34