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Endoplasmic reticulum degradation impedes olfactory G-protein coupled receptor functional expression
BACKGROUND: Research on olfactory G-protein coupled receptors (GPCRs) has been severely impeded by poor functional expression in heterologous systems. Previously, we demonstrated that inefficient olfactory receptor (OR) expression at the plasma membrane is attributable, in part, to degradation of en...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC520810/ https://www.ncbi.nlm.nih.gov/pubmed/15369603 http://dx.doi.org/10.1186/1471-2121-5-34 |