Characterization of a novel large deletion and single point mutations in the BRCA1 gene in a Greek cohort of families with suspected hereditary breast cancer

BACKGROUND: Germline mutations in BRCA1 and BRCA2 predispose to breast and ovarian cancer. A multitude of mutations have been described and are found to be scattered throughout these two large genes. We describe analysis of BRCA1 in 25 individuals from 18 families from a Greek cohort. METHODS: The a...

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Detalles Bibliográficos
Autores principales: Belogianni, Ioulia, Apessos, Angela, Mihalatos, Markos, Razi, Evangelia, Labropoulos, Stefanos, Petounis, Andreas, Gaki, Vasiliki, Keramopoulos, Antonios, Pandis, Nikos, Kyriacou, Kyriacos, Hadjisavvas, Andreas, Kosmidis, Paris, Yannoukakos, Drakoulis, Nasioulas, Georgios
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC520816/
https://www.ncbi.nlm.nih.gov/pubmed/15353005
http://dx.doi.org/10.1186/1471-2407-4-61

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC520816/
https://www.ncbi.nlm.nih.gov/pubmed/15353005
http://dx.doi.org/10.1186/1471-2407-4-61

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