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Cornea Lymphatics Drive the CD8(+) T Cell Response to Herpes Simplex Virus-1

Herpes simplex virus type 1 (HSV-1) infection of the cornea induces vascular endothelial growth factor (VEGF)-A-dependent lymphangiogenesis. However, the extent to which HSV-1-induced corneal lymphangiogenesis impacts the adaptive immune response has not been characterized. Here, we used floxed VEGF...

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Detalles Bibliográficos
Autores principales: Gurung, Hem R., Carr, Meghan M., Carr, Daniel J. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209249/
https://www.ncbi.nlm.nih.gov/pubmed/27577867
http://dx.doi.org/10.1038/icb.2016.80