Stat3 and C/EBPβ synergize to induce miR-21 and miR-181b expression during sepsis

Myeloid-derived suppressor cells (MDSCs) increase late sepsis immunosuppression and mortality in mice. We reported that microRNA (miR) 21 and miR-181b expression in Gr1(+)CD11b(+) myeloid progenitors increase septic MDSCs in mice by arresting macrophage and dendritic cell differentiation. Here, we r...

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Detalles Bibliográficos
Autores principales: McClure, Clara, McPeak, Melissa B., Youssef, Dima, Yao, Zhi Q., McCall, Charles E., El Gazzar, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209283/
https://www.ncbi.nlm.nih.gov/pubmed/27430527
http://dx.doi.org/10.1038/icb.2016.63

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209283/
https://www.ncbi.nlm.nih.gov/pubmed/27430527
http://dx.doi.org/10.1038/icb.2016.63

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