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Stat3 and C/EBPβ synergize to induce miR-21 and miR-181b expression during sepsis
Myeloid-derived suppressor cells (MDSCs) increase late sepsis immunosuppression and mortality in mice. We reported that microRNA (miR) 21 and miR-181b expression in Gr1(+)CD11b(+) myeloid progenitors increase septic MDSCs in mice by arresting macrophage and dendritic cell differentiation. Here, we r...
Autores principales: | McClure, Clara, McPeak, Melissa B., Youssef, Dima, Yao, Zhi Q., McCall, Charles E., El Gazzar, Mohamed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209283/ https://www.ncbi.nlm.nih.gov/pubmed/27430527 http://dx.doi.org/10.1038/icb.2016.63 |
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