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Genetic Variation in the Histamine Production, Response, and Degradation Pathway Is Associated with Histamine Pharmacodynamic Response in Children with Asthma

Introduction: There is growing knowledge of the wide ranging effects of histamine throughout the body therefore it is important to better understand the effects of this amine in patients with asthma. We aimed to explore the association between histamine pharmacodynamic (PD) response and genetic vari...

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Detalles Bibliográficos
Autores principales: Jones, Bridgette L., Sherwin, Catherine M. T., Liu, Xiaoxi, Dai, Hongying, Vyhlidal, Carrie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209333/
https://www.ncbi.nlm.nih.gov/pubmed/28101058
http://dx.doi.org/10.3389/fphar.2016.00524