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Endoplasmic Reticulum Protein Quality Control Failure in Myelin Disorders
Reaching the correct three-dimensional structure is crucial for the proper function of a protein. The endoplasmic reticulum (ER) is the organelle where secreted and transmembrane proteins are synthesized and folded. To guarantee high fidelity of protein synthesis and maturation in the ER, cells have...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209374/ https://www.ncbi.nlm.nih.gov/pubmed/28101003 http://dx.doi.org/10.3389/fnmol.2016.00162 |