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Endoplasmic Reticulum Protein Quality Control Failure in Myelin Disorders
Reaching the correct three-dimensional structure is crucial for the proper function of a protein. The endoplasmic reticulum (ER) is the organelle where secreted and transmembrane proteins are synthesized and folded. To guarantee high fidelity of protein synthesis and maturation in the ER, cells have...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209374/ https://www.ncbi.nlm.nih.gov/pubmed/28101003 http://dx.doi.org/10.3389/fnmol.2016.00162 |