Knockout of Lysosomal Enzyme-Targeting Gene Causes Abnormalities in Mouse Pup Isolation Calls

Humans lacking a working copy of the GNPTAB gene suffer from the metabolic disease Mucolipidosis type II (MLII). MLII symptoms include mental retardation, skeletal deformities and cartilage defects as well as a speech delay with most subjects unable to utter single words (Otomo et al., 2009; Cathey...

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Detalles Bibliográficos
Autores principales: Barnes, Terra D., Holy, Timothy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209381/
https://www.ncbi.nlm.nih.gov/pubmed/28101008
http://dx.doi.org/10.3389/fnbeh.2016.00237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209381/
https://www.ncbi.nlm.nih.gov/pubmed/28101008
http://dx.doi.org/10.3389/fnbeh.2016.00237

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