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Fluorescent Affibody Molecule Administered In Vivo at a Microdose Level Labels EGFR Expressing Glioma Tumor Regions

PURPOSE: Fluorescence guidance in surgical oncology provides the potential to realize enhanced molecular tumor contrast with dedicated targeted tracers, potentially with a microdose injection level. For most glioma tumors, the blood brain barrier is compromised allowing some exogenous drug/molecule...

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Detalles Bibliográficos
Autores principales: de Souza, Ana Luiza Ribeiro, Marra, Kayla, Gunn, Jason, Samkoe, Kimberley S., Hoopes, P. Jack, Feldwisch, Joachim, Paulsen, Keith D., Pogue, Brian W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209393/
https://www.ncbi.nlm.nih.gov/pubmed/27379987
http://dx.doi.org/10.1007/s11307-016-0980-7