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Cytochrome P450-2E1 promotes fast food-mediated hepatic fibrosis

Cytochrome P450-2E1 (CYP2E1) increases oxidative stress. High hepatic cholesterol causes non-alcoholic steatohepatitis (NASH) and fibrosis. Thus, we aimed to study the role of CYP2E1 in promoting liver fibrosis by high cholesterol-containing fast-food (FF). Male wild-type (WT) and Cyp2e1-null mice w...

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Detalles Bibliográficos
Autores principales: Abdelmegeed, Mohamed A., Choi, Youngshim, Godlewski, Grzegorz, Ha, Seung-Kwon, Banerjee, Atrayee, Jang, Sehwan, Song, Byoung-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209674/
https://www.ncbi.nlm.nih.gov/pubmed/28051126
http://dx.doi.org/10.1038/srep39764