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Deep Transcriptomic Profiling of M1 Macrophages Lacking Trpc3

In previous studies using mice with macrophage-specific loss of TRPC3 we found a significant, selective effect of TRPC3 on the biology of M1, or inflammatory macrophages. Whereas activation of some components of the unfolded protein response and the pro-apoptotic mediators CamkII and Stat1 was impai...

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Detalles Bibliográficos
Autores principales: Kumarasamy, Sivarajan, Solanki, Sumeet, Atolagbe, Oluwatomisin T., Joe, Bina, Birnbaumer, Lutz, Vazquez, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209678/
https://www.ncbi.nlm.nih.gov/pubmed/28051144
http://dx.doi.org/10.1038/srep39867