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Deep Transcriptomic Profiling of M1 Macrophages Lacking Trpc3
In previous studies using mice with macrophage-specific loss of TRPC3 we found a significant, selective effect of TRPC3 on the biology of M1, or inflammatory macrophages. Whereas activation of some components of the unfolded protein response and the pro-apoptotic mediators CamkII and Stat1 was impai...
Autores principales: | Kumarasamy, Sivarajan, Solanki, Sumeet, Atolagbe, Oluwatomisin T., Joe, Bina, Birnbaumer, Lutz, Vazquez, Guillermo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209678/ https://www.ncbi.nlm.nih.gov/pubmed/28051144 http://dx.doi.org/10.1038/srep39867 |
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