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Ndfip1 restricts Th17 cell potency by limiting lineage stability and proinflammatory cytokine production

While Th17 cells can protect against colonization by pathogenic organisms, they also have the potential to become pathogenic and promote autoimmune and inflammatory diseases. Mechanisms that control their pathogenic potential remain poorly understood. Here we show that Ndfip1, a co-activator of the...

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Detalles Bibliográficos
Autores principales: Kesewa Layman, Awo Akosua, L. Sprout, Stephanie, Phillips, Dylan, Oliver, Paula M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209687/
https://www.ncbi.nlm.nih.gov/pubmed/28051111
http://dx.doi.org/10.1038/srep39649