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Ndfip1 restricts Th17 cell potency by limiting lineage stability and proinflammatory cytokine production
While Th17 cells can protect against colonization by pathogenic organisms, they also have the potential to become pathogenic and promote autoimmune and inflammatory diseases. Mechanisms that control their pathogenic potential remain poorly understood. Here we show that Ndfip1, a co-activator of the...
Autores principales: | Kesewa Layman, Awo Akosua, L. Sprout, Stephanie, Phillips, Dylan, Oliver, Paula M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209687/ https://www.ncbi.nlm.nih.gov/pubmed/28051111 http://dx.doi.org/10.1038/srep39649 |
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