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RNA synthesis is associated with multiple TBP-chromatin binding events

Competition ChIP is an experimental method that allows transcription factor (TF) chromatin turnover dynamics to be measured across a genome. We develop and apply a physical model of TF-chromatin competitive binding using chemical reaction rate theory and are able to derive the physical half-life or...

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Detalles Bibliográficos
Autores principales: Zaidi, Hussain A., Auble, David T., Bekiranov, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209698/
https://www.ncbi.nlm.nih.gov/pubmed/28051102
http://dx.doi.org/10.1038/srep39631