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β(2)-adrenoreceptor Inverse Agonist Down-regulates Muscarine Cholinergic Subtype-3 Receptor and Its Downstream Signal Pathways in Airway Smooth Muscle Cells in vitro

Mechanisms underlying β(2)-adrenoreceptor (β(2)AR) inverse agonist mediated bronchoprotectiveness remain unknown. We incubated ICI118,551, formoterol, budesonide, and formoterol plus budesonide, as well as ICI118,551 or pindolol plus formoterol, ICI118,551 plus forskolin, SQ22,536 or H89 plus formot...

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Detalles Bibliográficos
Autores principales: Luo, Jian, Liu, Yuan-hua, Luo, Wei, Luo, Zhu, Liu, Chun-tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209700/
https://www.ncbi.nlm.nih.gov/pubmed/28051147
http://dx.doi.org/10.1038/srep39905